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Community Reference Laboratory for Mycotoxins

The Regulation (EC) No 776/2006 nominates the Joint Research Centre as the Community reference laboratory (CRL) for mycotoxins. It is established at the JRC Institute for Reference Materials and Measurements (IRMM) and works together with appointed national reference laboratories (NRLs) of the EU Member States. The CRL for mycotoxins aims to facilitate the implementation of European legislation related to monitoring of mycotoxins in food of plant origin and animal feed.


What are mycotoxins?

Download the mycotoxin factsheet (icon 850KB ).

Mycotoxins are toxic metabolites produced by fungi growing in food and animal feed. As about 20 % of food products, mainly of plant origin, can be contaminated with mycotoxins, European legislation sets maximum limits to protect the consumers. To ensure that results from the laboratories monitoring food and feed fulfil the requirements of legislation, any method that is used for analysis of goods must meet established and accepted performance criteria. Therefore, the CRL for mycotoxins co-ordinates activities related to the development and improvement of methods of analysis for the official control of the maximum levels.

Tasks of the CRL for Mycotoxins

The main tasks of the CRL for mycotoxins are:
  • method development and validation
  • organising comparative testing
  • training
The activities of the CRL concern aflatoxin B1, total aflatoxins, ochratoxin A, patulin, deoxynivalenol, zearalenone, fumonisins B1 & B2 and T-2 & HT-2 toxin, and ergot alkaloids.

The IRMM and the CRL for mycotoxins develop analytical approaches and validate them in-house. In case a method is suitable and robust enough, the CRL organises an international collaborative study to validate the method and to assess the method performance. The collaborative studies are carried out according to an internationally harmonised validation protocol.

Interlaboratory comparisons organised by the CRL for the NRLs enable them to assess their performance and allow improving the overall correctness of analytical results for mycotoxins.



Last Update 09/06/2010